BDBM50211364 3-(3-fluorobenzyl)-1H-pyrazole-5-carboxylic acid::5-meta-fluorobenzyl-3-carboxyl-pyrazole::CHEMBL429495

SMILES: OC(=O)c1cc(Cc2cccc(F)c2)[nH]n1

InChI Key: InChIKey=DWGHGHIWIZJJKX-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50211364 (3-(3-fluorobenzyl)-1H-pyrazole-5-carboxylic acid |...) Show SMILES OC(=O)c1cc(Cc2cccc(F)c2)[nH]n1 Show InChI InChI=1S/C11H9FN2O2/c12-8-3-1-2-7(4-8)5-9-6-10(11(15)16)14-13-9/h1-4,6H,5H2,(H,13,14)(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonist activity at GPR109A receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced intracellular cAMP production by Flashplate...				J Biol Chem 282: 18028-36 (2007) Article DOI: 10.1074/jbc.M701866200 BindingDB Entry DOI: 10.7270/Q2BV7HJC
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50211364 (3-(3-fluorobenzyl)-1H-pyrazole-5-carboxylic acid |...) Show SMILES OC(=O)c1cc(Cc2cccc(F)c2)[nH]n1 Show InChI InChI=1S/C11H9FN2O2/c12-8-3-1-2-7(4-8)5-9-6-10(11(15)16)14-13-9/h1-4,6H,5H2,(H,13,14)(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test				Bioorg Med Chem Lett 17: 4914-9 (2007) Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M
					More data for this Ligand-Target Pair