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Enter Data

null

SMILES: CCNC(=O)N1CCC(CC1)Nc1nccc(n1)-c1cnc2ccccn12

InChI Key: InChIKey=WWHNHBJMWMVKHQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211427
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcription factor Jun (Homo sapiens (Human))	BDBM50211427 (4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of cJun translocation in IL1beta-stimulated A549 cells				Bioorg Med Chem Lett 17: 3463-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.078 BindingDB Entry DOI: 10.7270/Q2959H7W
UCB Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50211427 (4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of CDK2 by IMAP technology				Bioorg Med Chem Lett 17: 3463-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.078 BindingDB Entry DOI: 10.7270/Q2959H7W
UCB Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50211427 (4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of JNK1				Bioorg Med Chem Lett 17: 3463-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.078 BindingDB Entry DOI: 10.7270/Q2959H7W
UCB Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50211427 (4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	281	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of JNK2				Bioorg Med Chem Lett 17: 3463-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.078 BindingDB Entry DOI: 10.7270/Q2959H7W
UCB Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50211427 (4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of JNK3				Bioorg Med Chem Lett 17: 3463-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.078 BindingDB Entry DOI: 10.7270/Q2959H7W
UCB Curated by ChEMBL					More data for this Ligand-Target Pair