BDBM50211538 4-ethyl-N-((3S,4R)-3-hydroxy-2,2-dimethyl-6-((phenethylamino)methyl)chroman-4-yl)benzenesulfonamide::CHEMBL387950

SMILES: CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(CNCCc3ccccc3)cc12

InChI Key: InChIKey=RRFYNWHHWWURDL-SXOMAYOGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50211538 (4-ethyl-N-((3S,4R)-3-hydroxy-2,2-dimethyl-6-((phen...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(CNCCc3ccccc3)cc12 Show InChI InChI=1S/C28H34N2O4S/c1-4-20-10-13-23(14-11-20)35(32,33)30-26-24-18-22(12-15-25(24)34-28(2,3)27(26)31)19-29-17-16-21-8-6-5-7-9-21/h5-15,18,26-27,29-31H,4,16-17,19H2,1-3H3/t26-,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair