Found 3 hits for monomerid = 50211555 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50211555
(CHEMBL397679 | N-[(2,5-dichloro-benzylcarbamoyl)-m...)Show SMILES [O-][n+]1ccccc1CCC(NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cc(Cl)ccc1Cl |w:9.10| Show InChI InChI=1S/C25H26Cl2N4O5S/c26-20-9-11-22(27)19(14-20)15-28-24(32)16-29-25(33)23(12-10-21-8-4-5-13-31(21)34)30-37(35,36)17-18-6-2-1-3-7-18/h1-9,11,13-14,23,30H,10,12,15-17H2,(H,28,32)(H,29,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50211555
(CHEMBL397679 | N-[(2,5-dichloro-benzylcarbamoyl)-m...)Show SMILES [O-][n+]1ccccc1CCC(NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cc(Cl)ccc1Cl |w:9.10| Show InChI InChI=1S/C25H26Cl2N4O5S/c26-20-9-11-22(27)19(14-20)15-28-24(32)16-29-25(33)23(12-10-21-8-4-5-13-31(21)34)30-37(35,36)17-18-6-2-1-3-7-18/h1-9,11,13-14,23,30H,10,12,15-17H2,(H,28,32)(H,29,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50211555
(CHEMBL397679 | N-[(2,5-dichloro-benzylcarbamoyl)-m...)Show SMILES [O-][n+]1ccccc1CCC(NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cc(Cl)ccc1Cl |w:9.10| Show InChI InChI=1S/C25H26Cl2N4O5S/c26-20-9-11-22(27)19(14-20)15-28-24(32)16-29-25(33)23(12-10-21-8-4-5-13-31(21)34)30-37(35,36)17-18-6-2-1-3-7-18/h1-9,11,13-14,23,30H,10,12,15-17H2,(H,28,32)(H,29,33) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |