BDBM50211559 CHEMBL230360::ethyl 2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)carbamoyl)pyrrolidin-1-yl)-4-(4-hydroxyphenyl)-1-oxobutan-2-ylamino)acetate

SMILES: CCOC(=O)CN[C@H](CCc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CN

InChI Key: InChIKey=FVYGXQLKUXZGOL-RPWUZVMVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50211559 (CHEMBL230360 | ethyl 2-((R)-1-((S)-2-((2-(aminomet...) Show SMILES CCOC(=O)CN[C@H](CCc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CN Show InChI InChI=1S/C27H35ClN4O5/c1-2-37-25(34)17-30-23(12-7-18-5-10-22(33)11-6-18)27(36)32-13-3-4-24(32)26(35)31-16-20-14-21(28)9-8-19(20)15-29/h5-6,8-11,14,23-24,30,33H,2-4,7,12-13,15-17,29H2,1H3,(H,31,35)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 17: 3322-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50211559 (CHEMBL230360 | ethyl 2-((R)-1-((S)-2-((2-(aminomet...) Show SMILES CCOC(=O)CN[C@H](CCc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CN Show InChI InChI=1S/C27H35ClN4O5/c1-2-37-25(34)17-30-23(12-7-18-5-10-22(33)11-6-18)27(36)32-13-3-4-24(32)26(35)31-16-20-14-21(28)9-8-19(20)15-29/h5-6,8-11,14,23-24,30,33H,2-4,7,12-13,15-17,29H2,1H3,(H,31,35)/t23-,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a				Bioorg Med Chem Lett 17: 3322-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50211559 (CHEMBL230360 | ethyl 2-((R)-1-((S)-2-((2-(aminomet...) Show SMILES CCOC(=O)CN[C@H](CCc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CN Show InChI InChI=1S/C27H35ClN4O5/c1-2-37-25(34)17-30-23(12-7-18-5-10-22(33)11-6-18)27(36)32-13-3-4-24(32)26(35)31-16-20-14-21(28)9-8-19(20)15-29/h5-6,8-11,14,23-24,30,33H,2-4,7,12-13,15-17,29H2,1H3,(H,31,35)/t23-,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of uPA				Bioorg Med Chem Lett 17: 3322-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K
					More data for this Ligand-Target Pair