Found 3 hits for monomerid = 50211572 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50211572
((4-{[1-{[(2-aminomethyl-5-chloro-benzylcarbamoyl)-...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)CNC(=O)C(CCc1cccc[n+]1[O-])NS(=O)(=O)Cc1ccc(CC(O)=O)cc1 |w:17.18| Show InChI InChI=1S/C28H32ClN5O7S/c29-23-9-8-21(15-30)22(14-23)16-31-26(35)17-32-28(38)25(11-10-24-3-1-2-12-34(24)39)33-42(40,41)18-20-6-4-19(5-7-20)13-27(36)37/h1-9,12,14,25,33H,10-11,13,15-18,30H2,(H,31,35)(H,32,38)(H,36,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50211572
((4-{[1-{[(2-aminomethyl-5-chloro-benzylcarbamoyl)-...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)CNC(=O)C(CCc1cccc[n+]1[O-])NS(=O)(=O)Cc1ccc(CC(O)=O)cc1 |w:17.18| Show InChI InChI=1S/C28H32ClN5O7S/c29-23-9-8-21(15-30)22(14-23)16-31-26(35)17-32-28(38)25(11-10-24-3-1-2-12-34(24)39)33-42(40,41)18-20-6-4-19(5-7-20)13-27(36)37/h1-9,12,14,25,33H,10-11,13,15-18,30H2,(H,31,35)(H,32,38)(H,36,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50211572
((4-{[1-{[(2-aminomethyl-5-chloro-benzylcarbamoyl)-...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)CNC(=O)C(CCc1cccc[n+]1[O-])NS(=O)(=O)Cc1ccc(CC(O)=O)cc1 |w:17.18| Show InChI InChI=1S/C28H32ClN5O7S/c29-23-9-8-21(15-30)22(14-23)16-31-26(35)17-32-28(38)25(11-10-24-3-1-2-12-34(24)39)33-42(40,41)18-20-6-4-19(5-7-20)13-27(36)37/h1-9,12,14,25,33H,10-11,13,15-18,30H2,(H,31,35)(H,32,38)(H,36,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |