BDBM50211575 (R)-N-[(3-chloro-benzylcarbamoyl)-methyl]-4-(1-oxy-pyridin-2-yl)-2-phenylmethanesulfonylamino-butyramide::CHEMBL230981

SMILES: [O-][n+]1ccccc1CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cccc(Cl)c1

InChI Key: InChIKey=MEAGNALNYUREBU-HSZRJFAPSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50211575 ((R)-N-[(3-chloro-benzylcarbamoyl)-methyl]-4-(1-oxy...) Show SMILES [O-][n+]1ccccc1CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C25H27ClN4O5S/c26-21-10-6-9-20(15-21)16-27-24(31)17-28-25(32)23(13-12-22-11-4-5-14-30(22)33)29-36(34,35)18-19-7-2-1-3-8-19/h1-11,14-15,23,29H,12-13,16-18H2,(H,27,31)(H,28,32)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a				Bioorg Med Chem Lett 17: 3322-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50211575 ((R)-N-[(3-chloro-benzylcarbamoyl)-methyl]-4-(1-oxy...) Show SMILES [O-][n+]1ccccc1CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C25H27ClN4O5S/c26-21-10-6-9-20(15-21)16-27-24(31)17-28-25(32)23(13-12-22-11-4-5-14-30(22)33)29-36(34,35)18-19-7-2-1-3-8-19/h1-11,14-15,23,29H,12-13,16-18H2,(H,27,31)(H,28,32)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of uPA				Bioorg Med Chem Lett 17: 3322-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50211575 ((R)-N-[(3-chloro-benzylcarbamoyl)-methyl]-4-(1-oxy...) Show SMILES [O-][n+]1ccccc1CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C25H27ClN4O5S/c26-21-10-6-9-20(15-21)16-27-24(31)17-28-25(32)23(13-12-22-11-4-5-14-30(22)33)29-36(34,35)18-19-7-2-1-3-8-19/h1-11,14-15,23,29H,12-13,16-18H2,(H,27,31)(H,28,32)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 17: 3322-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K
					More data for this Ligand-Target Pair