Found 3 hits for monomerid = 50211581 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50211581
(2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)c...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCc1ccccn1)NCC(O)=O Show InChI InChI=1S/C24H30ClN5O4/c25-18-7-6-16(13-26)17(12-18)14-29-23(33)21-5-3-11-30(21)24(34)20(28-15-22(31)32)9-8-19-4-1-2-10-27-19/h1-2,4,6-7,10,12,20-21,28H,3,5,8-9,11,13-15,26H2,(H,29,33)(H,31,32)/t20-,21+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50211581
(2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)c...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCc1ccccn1)NCC(O)=O Show InChI InChI=1S/C24H30ClN5O4/c25-18-7-6-16(13-26)17(12-18)14-29-23(33)21-5-3-11-30(21)24(34)20(28-15-22(31)32)9-8-19-4-1-2-10-27-19/h1-2,4,6-7,10,12,20-21,28H,3,5,8-9,11,13-15,26H2,(H,29,33)(H,31,32)/t20-,21+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50211581
(2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)c...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCc1ccccn1)NCC(O)=O Show InChI InChI=1S/C24H30ClN5O4/c25-18-7-6-16(13-26)17(12-18)14-29-23(33)21-5-3-11-30(21)24(34)20(28-15-22(31)32)9-8-19-4-1-2-10-27-19/h1-2,4,6-7,10,12,20-21,28H,3,5,8-9,11,13-15,26H2,(H,29,33)(H,31,32)/t20-,21+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |