null

SMILES: NCCO.NCCO.OC(=O)c1ccccc1CCCCc1c([nH]c(=O)[nH]c1=O)C(O)=O

InChI Key: InChIKey=JHVWEDGWDZTMNH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211708   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50211708 (CHEMBL3910672) Show SMILES NCCO.NCCO.OC(=O)c1ccccc1CCCCc1c([nH]c(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C16H16N2O6/c19-13-11(12(15(22)23)17-16(24)18-13)8-4-2-6-9-5-1-3-7-10(9)14(20)21/h1,3,5,7H,2,4,6,8H2,(H,20,21)(H,22,23)(H2,17,18,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.19E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nagasaki University Curated by ChEMBL					Assay Description Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...				Bioorg Med Chem 25: 1465-1470 (2017) Article DOI: 10.1016/j.bmc.2017.01.009 BindingDB Entry DOI: 10.7270/Q2CC12TS
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50211708 (CHEMBL3910672) Show SMILES NCCO.NCCO.OC(=O)c1ccccc1CCCCc1c([nH]c(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C16H16N2O6/c19-13-11(12(15(22)23)17-16(24)18-13)8-4-2-6-9-5-1-3-7-10(9)14(20)21/h1,3,5,7H,2,4,6,8H2,(H,20,21)(H,22,23)(H2,17,18,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	638	n/a	n/a	n/a	n/a	n/a	n/a
Nagasaki University Curated by ChEMBL					Assay Description Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...				Bioorg Med Chem 25: 1465-1470 (2017) Article DOI: 10.1016/j.bmc.2017.01.009 BindingDB Entry DOI: 10.7270/Q2CC12TS
					More data for this Ligand-Target Pair