BDBM50211883 5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-3-methyl-2-thioxothiazolidin-4-one::CHEMBL228098

SMILES: CN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O

InChI Key: InChIKey=XTHRECBBXYAMLC-QPEQYQDCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-acyl-carrier protein reductase (Plasmodium falciparum)	BDBM50211883 (5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-3-...) Show SMILES CN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C15H9Cl2NO2S2/c1-18-14(19)13(22-15(18)21)7-9-3-5-12(20-9)10-4-2-8(16)6-11(10)17/h2-7H,1H3/b13-7-	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum recombinant enoyl ACP reductase expressed in BL21 (DE3) cells				J Med Chem 50: 2665-75 (2007) Article DOI: 10.1021/jm061257w BindingDB Entry DOI: 10.7270/Q2ZP46X9
					More data for this Ligand-Target Pair