BDBM50211918 CHEMBL226187::N-(5-chloro-2-hydroxyphenyl)-5-(4-methoxyphenyl)isoxazole-3-carboxamide::cid_17252838
SMILES: COc1ccc(cc1)-c1cc(no1)C(=O)Nc1cc(Cl)ccc1O
InChI Key: InChIKey=QCGLANSEHHDGNF-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human)) | BDBM50211918 (CHEMBL226187 | N-(5-chloro-2-hydroxyphenyl)-5-(4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2GM85XC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enoyl-acyl-carrier protein reductase (Plasmodium falciparum) | BDBM50211918 (CHEMBL226187 | N-(5-chloro-2-hydroxyphenyl)-5-(4-m...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum recombinant enoyl ACP reductase expressed in BL21 (DE3) cells | J Med Chem 50: 2665-75 (2007) Article DOI: 10.1021/jm061257w BindingDB Entry DOI: 10.7270/Q2ZP46X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human)) | BDBM50211918 (CHEMBL226187 | N-(5-chloro-2-hydroxyphenyl)-5-(4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2JD4VDZ | ||||||||||||
More data for this Ligand-Target Pair |