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BDBM50211935 5-((4-methoxynaphthalen-1-yl)methylene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one::CHEMBL227981

SMILES: COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(OC)c3ccccc23)C1=O

InChI Key: InChIKey=BUMMUFJVEANZMH-MOSHPQCFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211935   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Enoyl-acyl-carrier protein reductase


(Plasmodium falciparum)
BDBM50211935
PNG
(5-((4-methoxynaphthalen-1-yl)methylene)-3-(4-metho...)
Show SMILES COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(OC)c3ccccc23)C1=O
Show InChI InChI=1S/C22H17NO3S2/c1-25-16-10-8-15(9-11-16)23-21(24)20(28-22(23)27)13-14-7-12-19(26-2)18-6-4-3-5-17(14)18/h3-13H,1-2H3/b20-13-
PDB
MMDB

UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 870n/an/an/an/an/an/a



Institute of Science

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant enoyl ACP reductase expressed in BL21 (DE3) cells


J Med Chem 50: 2665-75 (2007)


Article DOI: 10.1021/jm061257w
BindingDB Entry DOI: 10.7270/Q2ZP46X9
More data for this
Ligand-Target Pair