BDBM50212028 2-(4-(2-hydroxyethyl)phenylamino)-4-phenylpyrimidine-5-carbonitrile::CHEMBL389343

SMILES: OCCc1ccc(Nc2ncc(C#N)c(n2)-c2ccccc2)cc1

InChI Key: InChIKey=VUISELUIGVHPLE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50212028 (2-(4-(2-hydroxyethyl)phenylamino)-4-phenylpyrimidi...) Show SMILES OCCc1ccc(Nc2ncc(C#N)c(n2)-c2ccccc2)cc1 Show InChI InChI=1S/C19H16N4O/c20-12-16-13-21-19(23-18(16)15-4-2-1-3-5-15)22-17-8-6-14(7-9-17)10-11-24/h1-9,13,24H,10-11H2,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2 activity				Bioorg Med Chem Lett 17: 3266-70 (2007) Article DOI: 10.1016/j.bmcl.2007.04.021 BindingDB Entry DOI: 10.7270/Q2GQ6XFG
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50212028 (2-(4-(2-hydroxyethyl)phenylamino)-4-phenylpyrimidi...) Show SMILES OCCc1ccc(Nc2ncc(C#N)c(n2)-c2ccccc2)cc1 Show InChI InChI=1S/C19H16N4O/c20-12-16-13-21-19(23-18(16)15-4-2-1-3-5-15)22-17-8-6-14(7-9-17)10-11-24/h1-9,13,24H,10-11H2,(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK1 activity				Bioorg Med Chem Lett 17: 3266-70 (2007) Article DOI: 10.1016/j.bmcl.2007.04.021 BindingDB Entry DOI: 10.7270/Q2GQ6XFG
					More data for this Ligand-Target Pair