BDBM50213240 1-(2,4-Dihydroxyphenyl)-3-[4-methoxy-3-(3-methylbut-2-enyl)phenyl]-prop-2-en-1-one::1-(2,4-dihydroxyphenyl)-3-[4-methoxy-3-(3-methylbut-2-enyl)-phenyl]prop-2-en-1-one::CHEMBL389925
SMILES: [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8])cc2-[#8])cc1-[#6]\[#6]=[#6](\[#6])-[#6]
InChI Key: InChIKey=POPCLQBIFPKBMG-BJMVGYQFSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 19A1 (Homo sapiens (Human)) | BDBM50213240 (1-(2,4-Dihydroxyphenyl)-3-[4-methoxy-3-(3-methylbu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human aromatase | J Med Chem 50: 2799-806 (2007) Article DOI: 10.1021/jm070109i BindingDB Entry DOI: 10.7270/Q2668F0Z | |||||||||||
More data for this Ligand-Target Pair |