BDBM50213566 2-(2,3-dihydro-1,4-benzodioxin-6-yl) acetic acid::CHEMBL235786
SMILES: OC(=O)Cc1ccc2OCCOc2c1
InChI Key: InChIKey=BVRNERFWPQRVJB-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase (Homo sapiens (Human)) | BDBM50213566 (2-(2,3-dihydro-1,4-benzodioxin-6-yl) acetic acid |...) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona Curated by ChEMBL | Assay Description Inhibition of COX2 in human whole blood after 15 mins | Bioorg Med Chem 15: 4876-90 (2007) Article DOI: 10.1016/j.bmc.2007.04.050 BindingDB Entry DOI: 10.7270/Q2VH5PN7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dehydrogenase/reductase SDR family member 9 (Rattus norvegicus) | BDBM50213566 (2-(2,3-dihydro-1,4-benzodioxin-6-yl) acetic acid |...) | Reactome pathway KEGG GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.18E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona Curated by ChEMBL | Assay Description Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reduction | Bioorg Med Chem 15: 4876-90 (2007) Article DOI: 10.1016/j.bmc.2007.04.050 BindingDB Entry DOI: 10.7270/Q2VH5PN7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50213566 (2-(2,3-dihydro-1,4-benzodioxin-6-yl) acetic acid |...) | PDB GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona Curated by ChEMBL | Assay Description Inhibition of COX1 in human whole blood after 15 mins | Bioorg Med Chem 15: 4876-90 (2007) Article DOI: 10.1016/j.bmc.2007.04.050 BindingDB Entry DOI: 10.7270/Q2VH5PN7 | |||||||||||
More data for this Ligand-Target Pair |