BDBM50213670 (S)-7-(2-(2-(2-(3,5-dimethylphenyl)-5-(2-(2-fluoro-6-(trifluoromethyl)phenyl)acetyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)propylamino)ethyl)-3-ethylquinazoline-2,4(1H,3H)-dione::CHEMBL232097

SMILES: CCn1c(=O)[nH]c2cc(CCNC[C@@H](C)c3c4CN(CCc4[nH]c3-c3cc(C)cc(C)c3)C(=O)Cc3c(F)cccc3C(F)(F)F)ccc2c1=O

InChI Key: InChIKey=JZNJQYJAQCLZEO-XMMPIXPASA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50213670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213670 ((S)-7-(2-(2-(2-(3,5-dimethylphenyl)-5-(2-(2-fluoro...) Show SMILES CCn1c(=O)[nH]c2cc(CCNC[C@@H](C)c3c4CN(CCc4[nH]c3-c3cc(C)cc(C)c3)C(=O)Cc3c(F)cccc3C(F)(F)F)ccc2c1=O Show InChI InChI=1S/C39H41F4N5O3/c1-5-48-37(50)27-10-9-25(18-33(27)46-38(48)51)11-13-44-20-24(4)35-29-21-47(34(49)19-28-30(39(41,42)43)7-6-8-31(28)40)14-12-32(29)45-36(35)26-16-22(2)15-23(3)17-26/h6-10,15-18,24,44-45H,5,11-14,19-21H2,1-4H3,(H,46,51)/t24-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHR				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50213670 ((S)-7-(2-(2-(2-(3,5-dimethylphenyl)-5-(2-(2-fluoro...) Show SMILES CCn1c(=O)[nH]c2cc(CCNC[C@@H](C)c3c4CN(CCc4[nH]c3-c3cc(C)cc(C)c3)C(=O)Cc3c(F)cccc3C(F)(F)F)ccc2c1=O Show InChI InChI=1S/C39H41F4N5O3/c1-5-48-37(50)27-10-9-25(18-33(27)46-38(48)51)11-13-44-20-24(4)35-29-21-47(34(49)19-28-30(39(41,42)43)7-6-8-31(28)40)14-12-32(29)45-36(35)26-16-22(2)15-23(3)17-26/h6-10,15-18,24,44-45H,5,11-14,19-21H2,1-4H3,(H,46,51)/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysis				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair