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SMILES: COc1ccc(cc1OC)C(SC[C@H](N)C(O)=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=MNTWBBGJJCVNIX-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213733   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50213733
PNG
((R)-2-amino-3-((3,4-dimethoxyphenyl)diphenylmethyl...)
Show SMILES COc1ccc(cc1OC)C(SC[C@H](N)C(O)=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H25NO4S/c1-28-21-14-13-19(15-22(21)29-2)24(17-9-5-3-6-10-17,18-11-7-4-8-12-18)30-16-20(25)23(26)27/h3-15,20H,16,25H2,1-2H3,(H,26,27)/t20-/m0/s1
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MMDB

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Similars
Article
PubMed
n/an/a 1.48E+4n/an/an/an/an/an/a



University of Shizuoka

Curated by ChEMBL


Assay Description
Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assay

Bioorg Med Chem Lett 17: 3921-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.101
BindingDB Entry DOI: 10.7270/Q2542N8R
More data for this
Ligand-Target Pair