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BDBM50213756 3-(2-bromo-phenylamino)-7-methyl-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL231710

SMILES: Cc1cc(O)c2N=C(Nc3ccccc3Br)NS(=O)(=O)c2c1

InChI Key: InChIKey=SEPLIUXYAAYEAK-UHFFFAOYSA-N

Data: 1 IC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213756   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50213756
PNG
(3-(2-bromo-phenylamino)-7-methyl-1,1-dioxo-1,4-dih...)
Show SMILES Cc1cc(O)c2N=C(Nc3ccccc3Br)NS(=O)(=O)c2c1 |t:6|
Show InChI InChI=1S/C14H12BrN3O3S/c1-8-6-11(19)13-12(7-8)22(20,21)18-14(17-13)16-10-5-3-2-4-9(10)15/h2-7,19H,1H3,(H2,16,17,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 280n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR


Bioorg Med Chem Lett 17: 3864-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.011
BindingDB Entry DOI: 10.7270/Q21C1WKG
More data for this
Ligand-Target Pair