BDBM50213757 3-(2-bromo-6-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL397869

SMILES: Oc1cc(Cl)cc2c1N=C(Nc1c(F)cccc1Br)NS2(=O)=O

InChI Key: InChIKey=MGNPAGUVQLDGRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50213757 (3-(2-bromo-6-fluoro-phenylamino)-7-chloro-1,1-diox...) Show SMILES Oc1cc(Cl)cc2c1N=C(Nc1c(F)cccc1Br)NS2(=O)=O |t:9| Show InChI InChI=1S/C13H8BrClFN3O3S/c14-7-2-1-3-8(16)11(7)17-13-18-12-9(20)4-6(15)5-10(12)23(21,22)19-13/h1-5,20H,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR				Bioorg Med Chem Lett 17: 3864-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.011 BindingDB Entry DOI: 10.7270/Q21C1WKG
					More data for this Ligand-Target Pair