BindingDB logo
myBDB logout

null

SMILES: Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1c(O)cccc1O)c2=O)C1CC1

InChI Key: InChIKey=RRZHUECSPPUENV-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha/2-beta


(Homo sapiens (Human))		BDBM50213799
PNG
(CHEMBL440642)
Show SMILES Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1c(O)cccc1O)c2=O)C1CC1
Show InChI InChI=1S/C26H22F2N2O3/c1-13-8-15(9-14(2)29-13)23-20(27)11-19-25(24(23)28)30(17-6-7-17)12-16(26(19)33)10-18-21(31)4-3-5-22(18)32/h3-5,8-9,11-12,17,31-32H,6-7,10H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
n/an/an/an/a 96n/an/an/an/a


TBA

Assay Description
Inhibitory activity against HeLa cell Topoisomerase II

Citation and Details

BindingDB Entry DOI: 10.7270/Q2TX3HJW
More data for this
Ligand-Target Pair