BDBM50214065 (1S,3S)-N1-((5-(benzyloxy)-1-methyl-1H-indol-3-yl)methyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclopentane-1,3-diamine::CHEMBL399734

SMILES: COc1ccc2c(C)cc(N[C@H]3CC[C@@H](C3)NCc3cn(C)c4ccc(OCc5ccccc5)cc34)nc2c1

InChI Key: InChIKey=VUBJBYTZSTWDPM-UIOOFZCWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50214065 ((1S,3S)-N1-((5-(benzyloxy)-1-methyl-1H-indol-3-yl)...) Show SMILES COc1ccc2c(C)cc(N[C@H]3CC[C@@H](C3)NCc3cn(C)c4ccc(OCc5ccccc5)cc34)nc2c1 Show InChI InChI=1S/C33H36N4O2/c1-22-15-33(36-31-18-27(38-3)11-13-29(22)31)35-26-10-9-25(16-26)34-19-24-20-37(2)32-14-12-28(17-30(24)32)39-21-23-7-5-4-6-8-23/h4-8,11-15,17-18,20,25-26,34H,9-10,16,19,21H2,1-3H3,(H,35,36)/t25-,26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4232-41 (2007) Article DOI: 10.1016/j.bmcl.2007.05.034 BindingDB Entry DOI: 10.7270/Q27W6BVC
					More data for this Ligand-Target Pair