BDBM50214128 4-(((1-(2,6-difluorobenzoyl)piperidin-4-yl)(2-(pyridin-2-yl)ethyl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL245956

SMILES: Cc1c(CN(CCc2ccccn2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C

InChI Key: InChIKey=QBWZPEOEGKGJMR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50214128 (4-(((1-(2,6-difluorobenzoyl)piperidin-4-yl)(2-(pyr...) Show SMILES Cc1c(CN(CCc2ccccn2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C Show InChI InChI=1S/C31H32F3N5O2/c1-21-26(30(40)39(36(21)2)25-11-9-22(32)10-12-25)20-38(17-13-23-6-3-4-16-35-23)24-14-18-37(19-15-24)31(41)29-27(33)7-5-8-28(29)34/h3-12,16,24H,13-15,17-20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma SA Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from CCR3 receptor in human eosinophils				Bioorg Med Chem Lett 17: 4228-31 (2007) Article DOI: 10.1016/j.bmcl.2007.05.035 BindingDB Entry DOI: 10.7270/Q2VQ32CH
					More data for this Ligand-Target Pair