BDBM50214203 (+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)-4-methoxybenzyl)butanoic acid::2-{3-[(2-fluoro-4-trifluoromethylbenzoylamino)-methyl]-4-methoxyphenylmethyl}butyric acid::CHEMBL387914

SMILES: CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O

InChI Key: InChIKey=BDLLIPYDNFENMY-UHFFFAOYSA-N

Data: 6 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50214203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50214203 ((+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido...) Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-13(20(28)29)8-12-4-7-18(30-2)14(9-12)11-26-19(27)16-6-5-15(10-17(16)22)21(23,24)25/h4-7,9-10,13H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Effect on PPARdelta transactivation activity in HEK293 cells				Bioorg Med Chem 15: 5177-90 (2007) Article DOI: 10.1016/j.bmc.2007.05.023 BindingDB Entry DOI: 10.7270/Q2QZ29P7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50214203 ((+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido...) Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-13(20(28)29)8-12-4-7-18(30-2)14(9-12)11-26-19(27)16-6-5-15(10-17(16)22)21(23,24)25/h4-7,9-10,13H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Effect on PPARgamma transactivation activity in HEK293 cells				Bioorg Med Chem 15: 5177-90 (2007) Article DOI: 10.1016/j.bmc.2007.05.023 BindingDB Entry DOI: 10.7270/Q2QZ29P7
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50214203 ((+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido...) Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-13(20(28)29)8-12-4-7-18(30-2)14(9-12)11-26-19(27)16-6-5-15(10-17(16)22)21(23,24)25/h4-7,9-10,13H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARgamma (unknown origin) transfected in HEK293 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 18: 4525-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.046 BindingDB Entry DOI: 10.7270/Q24X57KK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50214203 ((+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido...) Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-13(20(28)29)8-12-4-7-18(30-2)14(9-12)11-26-19(27)16-6-5-15(10-17(16)22)21(23,24)25/h4-7,9-10,13H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARalpha (unknown origin) transfected in HEK293 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 18: 4525-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.046 BindingDB Entry DOI: 10.7270/Q24X57KK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50214203 ((+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido...) Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-13(20(28)29)8-12-4-7-18(30-2)14(9-12)11-26-19(27)16-6-5-15(10-17(16)22)21(23,24)25/h4-7,9-10,13H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARdelta (unknown origin) transfected in HEK293 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 18: 4525-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.046 BindingDB Entry DOI: 10.7270/Q24X57KK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50214203 ((+/-)-2-(3-((2-fluoro-4-(trifluoromethyl)benzamido...) Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2F)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C21H21F4NO4/c1-3-13(20(28)29)8-12-4-7-18(30-2)14(9-12)11-26-19(27)16-6-5-15(10-17(16)22)21(23,24)25/h4-7,9-10,13H,3,8,11H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.20	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Effect on PPARalpha transactivation activity in HEK293 cells				Bioorg Med Chem 15: 5177-90 (2007) Article DOI: 10.1016/j.bmc.2007.05.023 BindingDB Entry DOI: 10.7270/Q2QZ29P7
					More data for this Ligand-Target Pair