BDBM50214431 8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid hydroxyamide::CHEMBL227119

SMILES: CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1

InChI Key: InChIKey=FJIZCQBWUCHHAR-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 10 (Homo sapiens (Human))	BDBM50214431 (8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...) Show SMILES CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1 Show InChI InChI=1S/C13H20N4O3/c1-17(2)11-5-3-10(4-6-11)9-15-13(19)14-8-7-12(18)16-20/h3-6,20H,7-9H2,1-2H3,(H,16,18)(H2,14,15,19)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50214431 (8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...) Show SMILES CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1 Show InChI InChI=1S/C13H20N4O3/c1-17(2)11-5-3-10(4-6-11)9-15-13(19)14-8-7-12(18)16-20/h3-6,20H,7-9H2,1-2H3,(H,16,18)(H2,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50214431 (8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...) Show SMILES CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1 Show InChI InChI=1S/C13H20N4O3/c1-17(2)11-5-3-10(4-6-11)9-15-13(19)14-8-7-12(18)16-20/h3-6,20H,7-9H2,1-2H3,(H,16,18)(H2,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	45.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50214431 (8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...) Show SMILES CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1 Show InChI InChI=1S/C13H20N4O3/c1-17(2)11-5-3-10(4-6-11)9-15-13(19)14-8-7-12(18)16-20/h3-6,20H,7-9H2,1-2H3,(H,16,18)(H2,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	492	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50214431 (8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...) Show SMILES CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1 Show InChI InChI=1S/C13H20N4O3/c1-17(2)11-5-3-10(4-6-11)9-15-13(19)14-8-7-12(18)16-20/h3-6,20H,7-9H2,1-2H3,(H,16,18)(H2,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair