BDBM50214435 4-Dimethylamino-N-[4-(2-mercapto-acetylamino)-butyl]-benzamide::4-dimethylamino-N-[4-(2-mercaptoacetylamino)butyl]benzamide::CHEMBL427510

SMILES: CN(C)c1ccc(cc1)C(=O)NCCCCNC(=O)CS

InChI Key: InChIKey=BTMXKFKUNIPMAH-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50214435 (4-Dimethylamino-N-[4-(2-mercapto-acetylamino)-buty...) Show SMILES CN(C)c1ccc(cc1)C(=O)NCCCCNC(=O)CS Show InChI InChI=1S/C15H23N3O2S/c1-18(2)13-7-5-12(6-8-13)15(20)17-10-4-3-9-16-14(19)11-21/h5-8,21H,3-4,9-11H2,1-2H3,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 10 (Homo sapiens (Human))	BDBM50214435 (4-Dimethylamino-N-[4-(2-mercapto-acetylamino)-buty...) Show SMILES CN(C)c1ccc(cc1)C(=O)NCCCCNC(=O)CS Show InChI InChI=1S/C15H23N3O2S/c1-18(2)13-7-5-12(6-8-13)15(20)17-10-4-3-9-16-14(19)11-21/h5-8,21H,3-4,9-11H2,1-2H3,(H,16,19)(H,17,20)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50214435 (4-Dimethylamino-N-[4-(2-mercapto-acetylamino)-buty...) Show SMILES CN(C)c1ccc(cc1)C(=O)NCCCCNC(=O)CS Show InChI InChI=1S/C15H23N3O2S/c1-18(2)13-7-5-12(6-8-13)15(20)17-10-4-3-9-16-14(19)11-21/h5-8,21H,3-4,9-11H2,1-2H3,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50214435 (4-Dimethylamino-N-[4-(2-mercapto-acetylamino)-buty...) Show SMILES CN(C)c1ccc(cc1)C(=O)NCCCCNC(=O)CS Show InChI InChI=1S/C15H23N3O2S/c1-18(2)13-7-5-12(6-8-13)15(20)17-10-4-3-9-16-14(19)11-21/h5-8,21H,3-4,9-11H2,1-2H3,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50214435 (4-Dimethylamino-N-[4-(2-mercapto-acetylamino)-buty...) Show SMILES CN(C)c1ccc(cc1)C(=O)NCCCCNC(=O)CS Show InChI InChI=1S/C15H23N3O2S/c1-18(2)13-7-5-12(6-8-13)15(20)17-10-4-3-9-16-14(19)11-21/h5-8,21H,3-4,9-11H2,1-2H3,(H,16,19)(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair