BDBM50214461 3-(2-(3-acetamidophenylamino)-8-cyanopyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-N-(2-(dimethylamino)ethyl)benzamide::CHEMBL230781

SMILES: CN(C)CCNC(=O)c1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(cnn23)C#N)c1

InChI Key: InChIKey=NBSVDPZIOKKIOZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50214461 (3-(2-(3-acetamidophenylamino)-8-cyanopyrazolo[1,5-...) Show SMILES CN(C)CCNC(=O)c1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(cnn23)C#N)c1 Show InChI InChI=1S/C25H26N10O2/c1-16(36)29-20-8-5-9-21(13-20)30-24-32-22-18(14-26)15-28-35(22)25(33-24)31-19-7-4-6-17(12-19)23(37)27-10-11-34(2)3/h4-9,12-13,15H,10-11H2,1-3H3,(H,27,37)(H,29,36)(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polaris Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human CK2 alpha				Bioorg Med Chem Lett 17: 4191-5 (2007) Article DOI: 10.1016/j.bmcl.2007.05.041 BindingDB Entry DOI: 10.7270/Q23778D9
					More data for this Ligand-Target Pair