BDBM50214870 5,6,7-trihydroxy-8-isobutyl-2-methyl-4H-chromen-4-one::CHEMBL226678

SMILES: CC(C)Cc1c(O)c(O)c(O)c2c1oc(C)cc2=O

InChI Key: InChIKey=ADNKLAAIRXDEOP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50214870 (5,6,7-trihydroxy-8-isobutyl-2-methyl-4H-chromen-4-...) Show SMILES CC(C)Cc1c(O)c(O)c(O)c2c1oc(C)cc2=O Show InChI InChI=1S/C14H16O5/c1-6(2)4-8-11(16)13(18)12(17)10-9(15)5-7(3)19-14(8)10/h5-6,16-18H,4H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-Bim peptide from human Bcl2 by fluorescence polarization assay				J Med Chem 50: 3163-6 (2007) Article DOI: 10.1021/jm070383c BindingDB Entry DOI: 10.7270/Q2NZ87BK
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50214870 (5,6,7-trihydroxy-8-isobutyl-2-methyl-4H-chromen-4-...) Show SMILES CC(C)Cc1c(O)c(O)c(O)c2c1oc(C)cc2=O Show InChI InChI=1S/C14H16O5/c1-6(2)4-8-11(16)13(18)12(17)10-9(15)5-7(3)19-14(8)10/h5-6,16-18H,4H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assay				Eur J Med Chem 59: 141-9 (2013) Article DOI: 10.1016/j.ejmech.2012.10.050 BindingDB Entry DOI: 10.7270/Q25B03V2
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50214870 (5,6,7-trihydroxy-8-isobutyl-2-methyl-4H-chromen-4-...) Show SMILES CC(C)Cc1c(O)c(O)c(O)c2c1oc(C)cc2=O Show InChI InChI=1S/C14H16O5/c1-6(2)4-8-11(16)13(18)12(17)10-9(15)5-7(3)19-14(8)10/h5-6,16-18H,4H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-Bim peptide from human Mcl1 by fluorescence polarization assay				J Med Chem 50: 3163-6 (2007) Article DOI: 10.1021/jm070383c BindingDB Entry DOI: 10.7270/Q2NZ87BK
					More data for this Ligand-Target Pair