BDBM50215124 CHEMBL104780

SMILES: Cc1noc(C)c1Cn1cc(C)c2ccc(cc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl

InChI Key: InChIKey=MZWJIDRFXJVDGC-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50215124 (CHEMBL104780) Show SMILES Cc1noc(C)c1Cn1cc(C)c2ccc(cc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl Show InChI InChI=1S/C21H18Cl2N4O3/c1-11-7-26(8-16-12(2)25-30-13(16)3)19-6-14(4-5-15(11)19)21(28)24-20-17(22)9-27(29)10-18(20)23/h4-7,9-10H,8H2,1-3H3,(H,24,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 8: 3053-8 (1998) BindingDB Entry DOI: 10.7270/Q2PV6NK6
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50215124 (CHEMBL104780) Show SMILES Cc1noc(C)c1Cn1cc(C)c2ccc(cc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl Show InChI InChI=1S/C21H18Cl2N4O3/c1-11-7-26(8-16-12(2)25-30-13(16)3)19-6-14(4-5-15(11)19)21(28)24-20-17(22)9-27(29)10-18(20)23/h4-7,9-10H,8H2,1-3H3,(H,24,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase type IV (PDE4) activity				Bioorg Med Chem Lett 8: 3053-8 (1998) BindingDB Entry DOI: 10.7270/Q2PV6NK6
					More data for this Ligand-Target Pair