BDBM50215138 CHEMBL317671

SMILES: Cc1nccc(n1)-c1c(ncn1CCCN1CCOCC1)-c1ccc(F)cc1

InChI Key: InChIKey=VHVNYPVBGUVDBF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 (Homo sapiens (Human))	BDBM50215138 (CHEMBL317671) Show SMILES Cc1nccc(n1)-c1c(ncn1CCCN1CCOCC1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H24FN5O/c1-16-23-8-7-19(25-16)21-20(17-3-5-18(22)6-4-17)24-15-27(21)10-2-9-26-11-13-28-14-12-26/h3-8,15H,2,9-14H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for inhibition of p38 MAP kinase				Bioorg Med Chem Lett 8: 3111-6 (1998) BindingDB Entry DOI: 10.7270/Q2FB554V
					More data for this Ligand-Target Pair