BDBM50215140 CHEMBL106669

SMILES: Cc1cc(cc(C)n1)-c1c(ncn1CCCN1CCOCC1)-c1ccc(F)cc1

InChI Key: InChIKey=RPGNTCCOEVQWIP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 (Homo sapiens (Human))	BDBM50215140 (CHEMBL106669) Show SMILES Cc1cc(cc(C)n1)-c1c(ncn1CCCN1CCOCC1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H27FN4O/c1-17-14-20(15-18(2)26-17)23-22(19-4-6-21(24)7-5-19)25-16-28(23)9-3-8-27-10-12-29-13-11-27/h4-7,14-16H,3,8-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for inhibition of p38 MAP kinase				Bioorg Med Chem Lett 8: 3111-6 (1998) BindingDB Entry DOI: 10.7270/Q2FB554V
					More data for this Ligand-Target Pair