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SMILES: CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3sc4ccccc4c3C)CCc2n(Cc2c(F)cccc2C(F)(F)F)c1=O

InChI Key: InChIKey=IUUWULWFDTYCPB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215168   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215168
PNG
(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(methy...)
Show SMILES CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3sc4ccccc4c3C)CCc2n(Cc2c(F)cccc2C(F)(F)F)c1=O
Show InChI InChI=1S/C35H35F4N5O2S/c1-23-25-9-3-4-12-31(25)47-32(23)22-42-17-14-30-27(20-42)33(45)43(19-18-41(2)16-13-24-8-5-6-15-40-24)34(46)44(30)21-26-28(35(37,38)39)10-7-11-29(26)36/h3-12,15H,13-14,16-22H2,1-2H3
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Similars
Article
PubMed
 10n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair