BDBM50215396 CHEMBL176654

SMILES: CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(OC(F)(F)F)cc3n2)c1)C(O)=O

InChI Key: InChIKey=PHPYDISUCJTNJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50215396 (CHEMBL176654) Show SMILES CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(OC(F)(F)F)cc3n2)c1)C(O)=O Show InChI InChI=1S/C25H25F3N2O5/c1-3-24(4-2,23(32)33)14-22(31)30-17-6-5-7-19(12-17)34-15-18-10-8-16-9-11-20(13-21(16)29-18)35-25(26,27)28/h5-13H,3-4,14-15H2,1-2H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro for antagonistic activity against LTD4 receptor in guinea pig ileum				Bioorg Med Chem Lett 8: 965-70 (1999) BindingDB Entry DOI: 10.7270/Q2V123XT
					More data for this Ligand-Target Pair