BDBM50215494 3-((dimethylamino)methyl)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL245461
SMILES: COc1ccc2[nH]c3C(NC(CN(C)C)Cc3c2c1)C(O)=O
InChI Key: InChIKey=MESXODUBVZGQCV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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MAP kinase-activated protein kinase 2 (Homo sapiens (Human)) | BDBM50215494 (3-((dimethylamino)methyl)-6-methoxy-2,3,4,9-tetrah...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of MK2 | Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC | |||||||||||
More data for this Ligand-Target Pair |