BDBM50215553 5-(2-(2-fluoromethyl)thiazole-4-yl)ethynyl)pyridine-3-carbonitrile::CHEMBL229962

SMILES: FCc1nc(cs1)C#Cc1cncc(c1)C#N

InChI Key: InChIKey=CPYKMPRWSNUWOQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50215553 (5-(2-(2-fluoromethyl)thiazole-4-yl)ethynyl)pyridin...) Show SMILES FCc1nc(cs1)C#Cc1cncc(c1)C#N Show InChI InChI=1S/C12H6FN3S/c13-4-12-16-11(8-17-12)2-1-9-3-10(5-14)7-15-6-9/h3,6-8H,4H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain membrane				J Med Chem 50: 3256-66 (2007) Article DOI: 10.1021/jm0701268 BindingDB Entry DOI: 10.7270/Q2FB52NB
					More data for this Ligand-Target Pair