BDBM50215557 4-amino-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide::CHEMBL230064

SMILES: Cc1ccc(NC(=O)c2ccc(N)c(c2)C(F)(F)F)cc1Nc1nccc(n1)-c1cccnc1

InChI Key: InChIKey=SAWAYEJQVOZQER-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50215557 (4-amino-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2...) Show SMILES Cc1ccc(NC(=O)c2ccc(N)c(c2)C(F)(F)F)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C24H19F3N6O/c1-14-4-6-17(31-22(34)15-5-7-19(28)18(11-15)24(25,26)27)12-21(14)33-23-30-10-8-20(32-23)16-3-2-9-29-13-16/h2-13H,28H2,1H3,(H,31,34)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
McGill University/Royal Victoria Hospital Curated by ChEMBL					Assay Description Inhibition of c-Abl				Bioorg Med Chem Lett 17: 4248-53 (2007) Article DOI: 10.1016/j.bmcl.2007.05.067 BindingDB Entry DOI: 10.7270/Q29K49XM
					More data for this Ligand-Target Pair