BDBM50215575 1-((3R,6S)-6-(3-(aminomethyl)phenyl)bicyclo[4.1.0]heptan-3-yl)-3-(3-chloro-4-fluorophenyl)-1-(2-(diisopropylamino)ethyl)urea::CHEMBL229177

SMILES: CC(C)N(CCN([C@@H]1CC[C@@]2(CC2C1)c1cccc(CN)c1)C(=O)Nc1ccc(F)c(Cl)c1)C(C)C

InChI Key: InChIKey=BLBIVZCHKCXNFE-NXRLCEILSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50215575 (1-((3R,6S)-6-(3-(aminomethyl)phenyl)bicyclo[4.1.0]...) Show SMILES CC(C)N(CCN([C@@H]1CC[C@@]2(CC2C1)c1cccc(CN)c1)C(=O)Nc1ccc(F)c(Cl)c1)C(C)C |w:12.13| Show InChI InChI=1S/C29H40ClFN4O/c1-19(2)34(20(3)4)12-13-35(28(36)33-24-8-9-27(31)26(30)16-24)25-10-11-29(17-23(29)15-25)22-7-5-6-21(14-22)18-32/h5-9,14,16,19-20,23,25H,10-13,15,17-18,32H2,1-4H3,(H,33,36)/t23?,25-,29-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in CHO cells				Bioorg Med Chem 15: 5369-85 (2007) Article DOI: 10.1016/j.bmc.2007.05.068 BindingDB Entry DOI: 10.7270/Q25T3K5V
					More data for this Ligand-Target Pair