BDBM50215625 3-(2,6-dichloropyridin-4-yl)-1-((3R,6S)-6-(3-(((S)-3-hydroxypyrrolidin-1-yl)methyl)phenyl)bicyclo[4.1.0]heptan-3-yl)-1-((1-(methylsulfonyl)piperidin-4-yl)methyl)urea::CHEMBL388972

SMILES: CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(CN3CC[C@H](O)C3)c2)C(=O)Nc2cc(Cl)nc(Cl)c2)CC1

InChI Key: InChIKey=HQSKPDKYNHSDCK-NXCHCBTASA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50215625 (3-(2,6-dichloropyridin-4-yl)-1-((3R,6S)-6-(3-(((S)...) Show SMILES CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(CN3CC[C@H](O)C3)c2)C(=O)Nc2cc(Cl)nc(Cl)c2)CC1 |w:15.14| Show InChI InChI=1S/C31H41Cl2N5O4S/c1-43(41,42)37-11-6-21(7-12-37)19-38(30(40)34-25-15-28(32)35-29(33)16-25)26-5-9-31(17-24(31)14-26)23-4-2-3-22(13-23)18-36-10-8-27(39)20-36/h2-4,13,15-16,21,24,26-27,39H,5-12,14,17-20H2,1H3,(H,34,35,40)/t24?,26-,27+,31-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Cartagena Curated by ChEMBL					Assay Description Antagonist activity at MCH1 receptor				Eur J Med Chem 45: 4509-22 (2010) Article DOI: 10.1016/j.ejmech.2010.07.011 BindingDB Entry DOI: 10.7270/Q2FT8N9V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50215625 (3-(2,6-dichloropyridin-4-yl)-1-((3R,6S)-6-(3-(((S)...) Show SMILES CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(CN3CC[C@H](O)C3)c2)C(=O)Nc2cc(Cl)nc(Cl)c2)CC1 |w:15.14| Show InChI InChI=1S/C31H41Cl2N5O4S/c1-43(41,42)37-11-6-21(7-12-37)19-38(30(40)34-25-15-28(32)35-29(33)16-25)26-5-9-31(17-24(31)14-26)23-4-2-3-22(13-23)18-36-10-8-27(39)20-36/h2-4,13,15-16,21,24,26-27,39H,5-12,14,17-20H2,1H3,(H,34,35,40)/t24?,26-,27+,31-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in CHO cells				Bioorg Med Chem 15: 5369-85 (2007) Article DOI: 10.1016/j.bmc.2007.05.068 BindingDB Entry DOI: 10.7270/Q25T3K5V
					More data for this Ligand-Target Pair