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SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C1/CCN(C1=O)c1ccccc1

InChI Key: InChIKey=VDIRQCDDCGAGET-DHZHZOJOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215735   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50215735
PNG
(CHEMBL295135)
Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C1/CCN(C1=O)c1ccccc1
Show InChI InChI=1S/C20H14Cl2N2O3/c21-12-9-15(22)17-14(18(20(26)27)23-16(17)10-12)8-11-6-7-24(19(11)25)13-4-2-1-3-5-13/h1-5,8-10,23H,6-7H2,(H,26,27)/b11-8+
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 31.6n/an/an/an/an/an/an/an/a



GlaxoWellcome S.p.A.

Curated by ChEMBL


Assay Description
In vitro affinity of compound for the glycinergic site associated with NMDA receptor was assessed by inhibition of the binding of [3H]glycine

Bioorg Med Chem Lett 8: 1689-92 (1998)


BindingDB Entry DOI: 10.7270/Q2WH2S5C
More data for this
Ligand-Target Pair