BDBM50215928 4-(4-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine::CHEMBL231012

SMILES: Nc1nc2c(nccc2[nH]1)-c1cc(Br)c[nH]1

InChI Key: InChIKey=PZVQODCOQPBJAM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50215928 (4-(4-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridi...) Show SMILES Nc1nc2c(nccc2[nH]1)-c1cc(Br)c[nH]1 Show InChI InChI=1S/C10H8BrN5/c11-5-3-7(14-4-5)8-9-6(1-2-13-8)15-10(12)16-9/h1-4,14H,(H3,12,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human MMP12 catalytic domain				Bioorg Med Chem Lett 19: 5461-3 (2009) Article DOI: 10.1016/j.bmcl.2009.07.099 BindingDB Entry DOI: 10.7270/Q2HX1CRC
					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50215928 (4-(4-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridi...) Show SMILES Nc1nc2c(nccc2[nH]1)-c1cc(Br)c[nH]1 Show InChI InChI=1S/C10H8BrN5/c11-5-3-7(14-4-5)8-9-6(1-2-13-8)15-10(12)16-9/h1-4,14H,(H3,12,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MMP12				Bioorg Med Chem Lett 17: 4495-9 (2007) Article DOI: 10.1016/j.bmcl.2007.06.005 BindingDB Entry DOI: 10.7270/Q2MW2GVX
					More data for this Ligand-Target Pair