BDBM50216014 6-(benzamidomethyl)-N-hydroxybenzo[b]thiophene-2-carboxamide::CHEMBL245364

SMILES: ONC(=O)c1cc2ccc(CNC(=O)c3ccccc3)cc2s1

InChI Key: InChIKey=JQVJXWAPKIYOCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216014 (6-(benzamidomethyl)-N-hydroxybenzo[b]thiophene-2-c...) Show SMILES ONC(=O)c1cc2ccc(CNC(=O)c3ccccc3)cc2s1 Show InChI InChI=1S/C17H14N2O3S/c20-16(12-4-2-1-3-5-12)18-10-11-6-7-13-9-15(17(21)19-22)23-14(13)8-11/h1-9,22H,10H2,(H,18,20)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 17: 4562-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.091 BindingDB Entry DOI: 10.7270/Q2CC10C4
					More data for this Ligand-Target Pair