BDBM50216428 CHEMBL393632::N-(4-(3,4-dichlorobenzamido)benzyl)-N,N-dimethyl(tetrahydro-2H-pyran-4-yl)methanaminium

SMILES: C[N+](C)(CC1CCOCC1)Cc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=WZFXYQUWHHPOHX-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50216428 (CHEMBL393632 | N-(4-(3,4-dichlorobenzamido)benzyl)...) Show SMILES C[N+](C)(CC1CCOCC1)Cc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C22H26Cl2N2O2/c1-26(2,15-17-9-11-28-12-10-17)14-16-3-6-19(7-4-16)25-22(27)18-5-8-20(23)21(24)13-18/h3-8,13,17H,9-12,14-15H2,1-2H3/p+1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cells				Bioorg Med Chem Lett 17: 4382-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.115 BindingDB Entry DOI: 10.7270/Q2F47NVR
					More data for this Ligand-Target Pair