BDBM50216440 CHEMBL436822::N-(4-(3-cyanobenzamido)benzyl)-N,N-dimethyl-tetrahydro-2H-pyran-4-aminium

SMILES: C[N+](C)(Cc1ccc(NC(=O)c2cccc(c2)C#N)cc1)C1CCOCC1

InChI Key: InChIKey=WINCCWBSWUPBFJ-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216440   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50216440 (CHEMBL436822 | N-(4-(3-cyanobenzamido)benzyl)-N,N-...) Show SMILES C[N+](C)(Cc1ccc(NC(=O)c2cccc(c2)C#N)cc1)C1CCOCC1 Show InChI InChI=1S/C22H25N3O2/c1-25(2,21-10-12-27-13-11-21)16-17-6-8-20(9-7-17)24-22(26)19-5-3-4-18(14-19)15-23/h3-9,14,21H,10-13,16H2,1-2H3/p+1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cells				Bioorg Med Chem Lett 17: 4382-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.115 BindingDB Entry DOI: 10.7270/Q2F47NVR
					More data for this Ligand-Target Pair