BDBM50216449 CHEMBL396571::N-(4-(3-(3-fluorophenyl)acrylamido)benzyl)-N,N-dimethyl-tetrahydro-2H-pyran-4-aminium

SMILES: C[N+](C)(Cc1ccc(NC(=O)\C=C\c2cccc(F)c2)cc1)C1CCOCC1

InChI Key: InChIKey=CKDJUYZJEQUUGO-DHZHZOJOSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50216449 (CHEMBL396571 | N-(4-(3-(3-fluorophenyl)acrylamido)...) Show SMILES C[N+](C)(Cc1ccc(NC(=O)\C=C\c2cccc(F)c2)cc1)C1CCOCC1 Show InChI InChI=1S/C23H27FN2O2/c1-26(2,22-12-14-28-15-13-22)17-19-6-9-21(10-7-19)25-23(27)11-8-18-4-3-5-20(24)16-18/h3-11,16,22H,12-15,17H2,1-2H3/p+1/b11-8+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cells				Bioorg Med Chem Lett 17: 4382-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.115 BindingDB Entry DOI: 10.7270/Q2F47NVR
					More data for this Ligand-Target Pair