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BDBM50216537 3-benzyl-1H-pyrazole-5-carboxylic acid::5-Benzyl-1H-pyrazole-3-carboxylic acid::CHEMBL247317

SMILES: OC(=O)c1cc(Cc2ccccc2)[nH]n1

InChI Key: InChIKey=YYEOXPLPYNYVRY-UHFFFAOYSA-N

Data: 1 KI  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216537   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Rattus norvegicus)
BDBM50216537
PNG
(3-benzyl-1H-pyrazole-5-carboxylic acid | 5-Benzyl-...)
Show SMILES OC(=O)c1cc(Cc2ccccc2)[nH]n1
Show InChI InChI=1S/C11H10N2O2/c14-11(15)10-7-9(12-13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,12,13)(H,14,15)
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PC sid
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Article
PubMed
1.25E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.


J Med Chem 46: 3945-51 (2003)

More data for this
Ligand-Target Pair
Hydroxycarboxylic acid receptor 2


(Homo sapiens (human))
BDBM50216537
PNG
(3-benzyl-1H-pyrazole-5-carboxylic acid | 5-Benzyl-...)
Show SMILES OC(=O)c1cc(Cc2ccccc2)[nH]n1
Show InChI InChI=1S/C11H10N2O2/c14-11(15)10-7-9(12-13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,12,13)(H,14,15)
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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 8.90E+3n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test


Bioorg Med Chem Lett 17: 4914-9 (2007)

More data for this
Ligand-Target Pair