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BDBM50216594 5-chloro-N-(1-(4-(2-oxopyridin-1(2H)-yl)benzamido)propan-2-yl)thiophene-2-carboxamide::CHEMBL393421

SMILES: CC(CNC(=O)c1ccc(cc1)-n1ccccc1=O)NC(=O)c1ccc(Cl)s1

InChI Key: InChIKey=KTTSAVNJPHPJHW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216594   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50216594
PNG
(5-chloro-N-(1-(4-(2-oxopyridin-1(2H)-yl)benzamido)...)
Show SMILES CC(CNC(=O)c1ccc(cc1)-n1ccccc1=O)NC(=O)c1ccc(Cl)s1 |w:1.0|
Show InChI InChI=1S/C20H18ClN3O3S/c1-13(23-20(27)16-9-10-17(21)28-16)12-22-19(26)14-5-7-15(8-6-14)24-11-3-2-4-18(24)25/h2-11,13H,12H2,1H3,(H,22,26)(H,23,27)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
1.70n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 4419-27 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.029
BindingDB Entry DOI: 10.7270/Q2416XVV
More data for this
Ligand-Target Pair