BDBM50216624 CHEMBL232969::cis-N-(2-((5-chlorothiophen-2-yl)methylamino)cyclopentyl)-4-(2-oxopyridin-1(2H)-yl)benzamide

SMILES: Clc1ccc(CN[C@@H]2CCC[C@@H]2NC(=O)c2ccc(cc2)-n2ccccc2=O)s1

InChI Key: InChIKey=BVLYCYKVFCIEDX-MOPGFXCFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50216624 (CHEMBL232969 | cis-N-(2-((5-chlorothiophen-2-yl)me...) Show SMILES Clc1ccc(CN[C@@H]2CCC[C@@H]2NC(=O)c2ccc(cc2)-n2ccccc2=O)s1 Show InChI InChI=1S/C22H22ClN3O2S/c23-20-12-11-17(29-20)14-24-18-4-3-5-19(18)25-22(28)15-7-9-16(10-8-15)26-13-2-1-6-21(26)27/h1-2,6-13,18-19,24H,3-5,14H2,(H,25,28)/t18-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
					More data for this Ligand-Target Pair