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SMILES: Cc1ccc2ccc(cc2n1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=QOWZEBQBRAXSAL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216751   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50216751
PNG
(2-methyl-7-(3-(trifluoromethyl)phenyl)quinoline | ...)
Show SMILES Cc1ccc2ccc(cc2n1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H12F3N/c1-11-5-6-12-7-8-14(10-16(12)21-11)13-3-2-4-15(9-13)17(18,19)20/h2-10H,1H3
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 17: 4415-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.030
BindingDB Entry DOI: 10.7270/Q28G8KDC
More data for this
Ligand-Target Pair