BDBM50216859 CHEMBL442232::{2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate
SMILES: CC(C)CC(C\C=C1\OC(CO)(COC(=O)C(C)(C)C)OC1=O)CC(C)C
InChI Key: InChIKey=FNAVULFGMYGNQE-RQZCQDPDSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C delta (Mus musculus) | BDBM50216859 (CHEMBL442232 | {2-(hydroxymethyl)-5-[5-methyl-3-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coli | J Med Chem 50: 3465-81 (2007) Article DOI: 10.1021/jm0702579 BindingDB Entry DOI: 10.7270/Q2RF5TQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta (Mus musculus) | BDBM50216859 (CHEMBL442232 | {2-(hydroxymethyl)-5-[5-methyl-3-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Binding affinity to mouse wildtype PKCdelta C1a expressed in Escherichia coli | J Med Chem 50: 3465-81 (2007) Article DOI: 10.1021/jm0702579 BindingDB Entry DOI: 10.7270/Q2RF5TQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C (MOUSE) | BDBM50216859 (CHEMBL442232 | {2-(hydroxymethyl)-5-[5-methyl-3-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coli | J Med Chem 50: 3465-81 (2007) Article DOI: 10.1021/jm0702579 BindingDB Entry DOI: 10.7270/Q2RF5TQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta (Mus musculus) | BDBM50216859 (CHEMBL442232 | {2-(hydroxymethyl)-5-[5-methyl-3-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Binding affinity to mouse PKC delta C1a Q27E mutant expressed in Escherichia coli | J Med Chem 50: 3465-81 (2007) Article DOI: 10.1021/jm0702579 BindingDB Entry DOI: 10.7270/Q2RF5TQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta (Mus musculus) | BDBM50216859 (CHEMBL442232 | {2-(hydroxymethyl)-5-[5-methyl-3-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Displacement of [3H]PDBu from mouse PKCdelta C1b Q27E mutant expressed in Escherichia coli | J Med Chem 50: 3465-81 (2007) Article DOI: 10.1021/jm0702579 BindingDB Entry DOI: 10.7270/Q2RF5TQ5 | |||||||||||
More data for this Ligand-Target Pair |