BDBM50216926 CHEMBL236478::l-2-((S)-1-phenyl-ethylamino)-1-oxa-3,8-diaza-spiro[4.5]dec-2-en-4-one

SMILES: C[C@H](NC1=NC(=O)C2(CCN(Cc3ccccc3)CC2)O1)c1ccccc1

InChI Key: InChIKey=NRFWFEMHRJCYJM-KRWDZBQOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50216926 (CHEMBL236478 | l-2-((S)-1-phenyl-ethylamino)-1-oxa...) Show SMILES C[C@H](NC1=NC(=O)C2(CCN(Cc3ccccc3)CC2)O1)c1ccccc1 |t:3| Show InChI InChI=1S/C22H25N3O2/c1-17(19-10-6-3-7-11-19)23-21-24-20(26)22(27-21)12-14-25(15-13-22)16-18-8-4-2-5-9-18/h2-11,17H,12-16H2,1H3,(H,23,24,26)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biovitrum AB Curated by ChEMBL					Assay Description Binding affinity to human 11beta-HSD1 by SPA assay				Bioorg Med Chem Lett 17: 4837-40 (2007) Article DOI: 10.1016/j.bmcl.2007.06.054 BindingDB Entry DOI: 10.7270/Q2MP52ZC
					More data for this Ligand-Target Pair