BDBM50217031 (1S,2R)-1-amino-2-phosphonomethylcyclopropane-carboxylic acid::CHEMBL229697

SMILES: N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O

InChI Key: InChIKey=RACNCOSUCJNQDH-UCORVYFPSA-N

Data: 2 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50217031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Univ. Rouen Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assay				Bioorg Med Chem Lett 25: 2523-6 (2015) Article DOI: 10.1016/j.bmcl.2015.04.043 BindingDB Entry DOI: 10.7270/Q21Z464C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at mGlu4 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
					More data for this Ligand-Target Pair
NMDA receptor subunit N2A (GluN2A) (Rattus norvegicus (Rat))	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat recombinant NMDA NR2A receptor expressed in xenopus laevis oocyte assessed as inhibition of glycine-stimulated current				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
					More data for this Ligand-Target Pair
GRM8 (Homo sapiens (Human))	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at mGlu8 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
					More data for this Ligand-Target Pair
GRM7 (Homo sapiens (Human))	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.02E+5	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at mGlu7 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50217031 ((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...) Show SMILES N[C@]1(C[C@H]1CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-5(4(7)8)1-3(5)2-12(9,10)11/h3H,1-2,6H2,(H,7,8)(H2,9,10,11)/t3-,5-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat recombinant NMDA NR1 receptor expressed in xenopus laevis oocyte assessed as inhibition of L-glutamate-stimulated current				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
					More data for this Ligand-Target Pair